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Heart: cardiac tamponade secondary to rupture of the left ventricle in a patient with an AMI At the apex of the heart, there is a rupture site in the area of a transmural AMI. Blood fills the pericardial sac and encircles the heart

Heart: cardiac tamponade secondary to rupture of the left ventricle in a patient with an AMI 
At the apex of the heart, there is a rupture site in the area of a transmural AMI. Blood fills the pericardial sac and encircles the heart

Heart: microscopic section of a 3 day old acute myocardial infarctionUnlike the previous slide, which showed the early stages of coagulation necrosis, this slide depicts a heavy neutrophilic infiltrate with destruction of the cardiac fibers. The neutrophils came into the area of the infarct from the periphery, so this should not be confused with liquefactive necrosis. Macrophages will eventually replace the neutrophils and then collagen tissue will be deposited in the area of infarction.

Heart: microscopic section of a 3 day old acute myocardial infarction
Unlike the previous slide, which showed the early stages of coagulation necrosis, this slide depicts a heavy neutrophilic infiltrate with destruction of the cardiac fibers. The neutrophils came into the area of the infarct from the periphery, so this should not be confused with liquefactive necrosis. Macrophages will eventually replace the neutrophils and then collagen tissue will be deposited in the area of infarction.

Heart: mitral valve prolapse Note the baggy-appearing mitral valve leaflets. When blood collects beneath these voluminous valves, it projects them into the left atrium like a parachute. When the chordae abruptly stop the valves from moving any further, a systolic click is heard followed by a murmur of mitral insufficiency.

Heart: mitral valve prolapse 
Note the baggy-appearing mitral valve leaflets. When blood collects beneath these voluminous valves, it projects them into the left atrium like a parachute. When the chordae abruptly stop the valves from moving any further, a systolic click is heard followed by a murmur of mitral insufficiency.

Children: cyanotic congenital heart diseaseNote the blue discoloration of the lips in these two children, both of which have tetralogy of Fallot. Refer to course notes for why these patients squat to relieve cyanosis. 

Children: cyanotic congenital heart disease
Note the blue discoloration of the lips in these two children, both of which have tetralogy of Fallot. Refer to course notes for why these patients squat to relieve cyanosis. 

Heart: right and left ventricular hypertrophy The left ventricle is on your left and the right ventricle on your right. Note that both ventricles are thickened. One possible explanation for RV hypertrophy is pulmonary artery hypertension, which imposes an increased afterload against the RV.

Heart: right and left ventricular hypertrophy 
The left ventricle is on your left and the right ventricle on your right. Note that both ventricles are thickened. One possible explanation for RV hypertrophy is pulmonary artery hypertension, which imposes an increased afterload against the RV.

Heart: coagulation necrosis of cardiac muscle in an AMINote the eosinophilic staining cells with no cross striations or nuclei.

Heart: coagulation necrosis of cardiac muscle in an AMI
Note the eosinophilic staining cells with no cross striations or nuclei.

Coronary artery: coronary artery atherosclerosis and thrombus occluding the lumen Note the red thrombus overlying an atheromatous plaque (arrow). The slit like spaces are where cholesterol used to be present.

Coronary artery: coronary artery atherosclerosis and thrombus occluding the lumen 
Note the red thrombus overlying an atheromatous plaque (arrow). The slit like spaces are where cholesterol used to be present.

Heart: heart with coronary artery bypasses using saphenous vein graftsNote the 2 veins, one bypassing the LAD coronary artery (arrow) and the other the RCA.

Heart: heart with coronary artery bypasses using saphenous vein grafts
Note the 2 veins, one bypassing the LAD coronary artery (arrow) and the other the RCA.

Right coronary artery angiogramRCA stenosis secondary to atherosclerosis. Note the area of constriction (arrow) in the mid-portion of the coronary artery.

Right coronary artery angiogram
RCA stenosis secondary to atherosclerosis. Note the area of constriction (arrow) in the mid-portion of the coronary artery.

Heart: cardiac tamponade secondary to rupture of the left ventricle in a patient with an AMI At the apex of the heart, there is a rupture site in the area of a transmural AMI. Blood fills the pericardial sac and encircles the heart

Heart: cardiac tamponade secondary to rupture of the left ventricle in a patient with an AMI 
At the apex of the heart, there is a rupture site in the area of a transmural AMI. Blood fills the pericardial sac and encircles the heart

Heart: microscopic section of a 3 day old acute myocardial infarctionUnlike the previous slide, which showed the early stages of coagulation necrosis, this slide depicts a heavy neutrophilic infiltrate with destruction of the cardiac fibers. The neutrophils came into the area of the infarct from the periphery, so this should not be confused with liquefactive necrosis. Macrophages will eventually replace the neutrophils and then collagen tissue will be deposited in the area of infarction.

Heart: microscopic section of a 3 day old acute myocardial infarction
Unlike the previous slide, which showed the early stages of coagulation necrosis, this slide depicts a heavy neutrophilic infiltrate with destruction of the cardiac fibers. The neutrophils came into the area of the infarct from the periphery, so this should not be confused with liquefactive necrosis. Macrophages will eventually replace the neutrophils and then collagen tissue will be deposited in the area of infarction.

Heart: mitral valve prolapse Note the baggy-appearing mitral valve leaflets. When blood collects beneath these voluminous valves, it projects them into the left atrium like a parachute. When the chordae abruptly stop the valves from moving any further, a systolic click is heard followed by a murmur of mitral insufficiency.

Heart: mitral valve prolapse 
Note the baggy-appearing mitral valve leaflets. When blood collects beneath these voluminous valves, it projects them into the left atrium like a parachute. When the chordae abruptly stop the valves from moving any further, a systolic click is heard followed by a murmur of mitral insufficiency.

Children: cyanotic congenital heart diseaseNote the blue discoloration of the lips in these two children, both of which have tetralogy of Fallot. Refer to course notes for why these patients squat to relieve cyanosis. 

Children: cyanotic congenital heart disease
Note the blue discoloration of the lips in these two children, both of which have tetralogy of Fallot. Refer to course notes for why these patients squat to relieve cyanosis. 

Heart: right and left ventricular hypertrophy The left ventricle is on your left and the right ventricle on your right. Note that both ventricles are thickened. One possible explanation for RV hypertrophy is pulmonary artery hypertension, which imposes an increased afterload against the RV.

Heart: right and left ventricular hypertrophy 
The left ventricle is on your left and the right ventricle on your right. Note that both ventricles are thickened. One possible explanation for RV hypertrophy is pulmonary artery hypertension, which imposes an increased afterload against the RV.

Heart: coagulation necrosis of cardiac muscle in an AMINote the eosinophilic staining cells with no cross striations or nuclei.

Heart: coagulation necrosis of cardiac muscle in an AMI
Note the eosinophilic staining cells with no cross striations or nuclei.

Coronary artery: coronary artery atherosclerosis and thrombus occluding the lumen Note the red thrombus overlying an atheromatous plaque (arrow). The slit like spaces are where cholesterol used to be present.

Coronary artery: coronary artery atherosclerosis and thrombus occluding the lumen 
Note the red thrombus overlying an atheromatous plaque (arrow). The slit like spaces are where cholesterol used to be present.

Heart: heart with coronary artery bypasses using saphenous vein graftsNote the 2 veins, one bypassing the LAD coronary artery (arrow) and the other the RCA.

Heart: heart with coronary artery bypasses using saphenous vein grafts
Note the 2 veins, one bypassing the LAD coronary artery (arrow) and the other the RCA.

Right coronary artery angiogramRCA stenosis secondary to atherosclerosis. Note the area of constriction (arrow) in the mid-portion of the coronary artery.

Right coronary artery angiogram
RCA stenosis secondary to atherosclerosis. Note the area of constriction (arrow) in the mid-portion of the coronary artery.

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